Mapping brain repair and remodeling after stroke

Researchers at Weill Cornell Medicine have catalogued the cellular response to stroke in a preclinical model, identifying the immune cells involved and the roles they may play in the days and weeks following a stroke.

Grants will fund tuberculosis drug development

Weill Cornell Medicine researchers and the TB Drug Accelerator have received two grants totaling $6.8 million from the Bill & Melinda Gates Foundation to study tuberculosis drug development.

3D organization of DNA controls cell identity programs

A new study reveals that beyond providing a convenient way to store DNA in a tight space, the 3D organization of noncoding gene regulators in chromatin contributes to the control of key cell identity programs in early embryonic development.

Aggressive colon tumor may be vulnerable to cholesterol therapy

A preclinical study has shown that colorectal pre-cancerous lesions known as serrated polyps, and the aggressive tumors that develop from them, depend on the ramped-up production of cholesterol, which points to the possibility of using cholesterol-lowering drugs to prevent or treat such tumors.

Discontinuing anti-obesity drug tirzepatide leads to weight regain

A clinical trial led by researchers at Weill Cornell Medicine and NewYork-Presbyterian found remaining on the anti-obesity drug tirzepatide promoted additional weight loss and preserved improvements in metabolic and cardiovascular health.

Team designing digital health tools for pregnant refugees wins NAM prize

An intercampus collaboration that aims to provide digital health care tools to pregnant refugee women, who are at elevated risk for pregnancy complications but often afraid to seek medical care, has been awarded a National Academy of Medicine Catalyst Prize.

Race doesn’t impact cardiovascular risk calculations

Removing race information from cardiovascular risk calculators – which predict the probability of developing heart disease – doesn’t affect patients’ risk scores, according to a study by Weill Cornell Medicine and NewYork-Presbyterian investigators.

Deep brain stimulation improves cognition after injury

Five people who had life-altering, seemingly irreversible cognitive deficits following moderate to severe traumatic brain injuries showed substantial improvements in their cognition and quality of life after receiving an experimental form of deep brain stimulation in a phase 1 clinical trial.

Method may improve cities’ responses to resident service calls

Researchers from Cornell Tech have developed a method to identify delays in the reporting of incidents such as downed trees and power lines, which could lead to practical insights and interventions for more equitable, efficient government service.