CRISPR insight: How to fine-tune the Cas protein’s grip on DNA

At the heart of every CRISPR reaction, whether naturally occurring in bacteria or harnessed by CRIPSR-Cas gene editing technology, is a strong molecular bond of a Cas protein via a guide RNA to its target site on DNA.

Pathogenic bacteria co-opt genetics to trigger Crohn’s

Changes in a single gene open the door for harmful gut bacteria to set off the inflammation that drives Crohn’s disease, according to a new study led by Weill Cornell Medicine and NewYork-Presbyterian investigators.

Experimental vaccines offer long-term protection against severe COVID

Researchers from Weill Cornell Medicine and colleagues found that two-dose vaccines still provide protection against lung disease in rhesus macaques a year after they had been vaccinated as infants.

Small fish could play big role in fight against malnutrition

Inexpensive, small fish species caught in seas and lakes in developing countries could help close nutritional gaps for undernourished people, and especially young children, according to new research.

Autism-linked gene shapes nerve connections

A gene linked to autism spectrum disorders plays a critical role in early brain development and may shape the formation of nerve connections in the brain.

Discovery suggests new way to target mantle cell lymphoma

A new study shows that blocking a certain protein's interaction with mantle cell lymphoma slows the growth of this cancer.

Machine learning gives nuanced view of Alzheimer’s stages

A Cornell-led collaboration used machine learning to pinpoint the most accurate means, and timelines, for anticipating the advancement of Alzheimer’s disease.

Appel ’53, vice chair of Weill Cornell Medicine board, dies at 91

Robert J. “Bob” Appel ’53, a vice chair of Weill Cornell Medicine’s Board of Fellows, Cornell trustee emeritus and presidential councillor, died Nov. 19 in New York, at age 91.

Cornell, global partners discuss the next ‘grand challenge’

More than 300 faculty, staff and students from Cornell and the new Cornell Global Hubs gathered Nov. 16-17 to discuss ideas for the next universitywide Global Grand Challenge.

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