Anticancer drugs could make immunotherapies more effective

An emerging class of anticancer drugs called EZH2 inhibitors may greatly enhance the potency of some cancer immunotherapies, according to a preclinical study led by Weill Cornell Medicine lymphoma researchers.

Cardiovascular disease symptoms high in young refugees

Many individuals seeking asylum in the United States show increased stress and pain symptoms that are associated with indications of cardiovascular disease, according to Weill Cornell Medicine researchers.

Good products can be hurt by experts’ tough ratings

Experts’ more stringent online reviews have the effect of compressing aggregate ratings by penalizing higher-quality products compared to their lower-quality alternatives. To address this problem, a research team developed a method for de-biasing ratings.

DNA secreted by tumor cell prompts immune response

Specially packaged DNA secreted by tumor cells can trigger an immune response that inhibits the metastatic spread of the tumor to the liver, according to a study led by researchers at Weill Cornell Medicine.

Study details mechanisms underlying severe COVID-19

Severe COVID-19 arises in part from the SARS-CoV-2 virus’s impact on mitochondria, tiny oxygen-burning power plants in cells, which can help trigger a cascade of organ- and immune system-damaging events, suggests a study by investigators at Weill Cornell Medicine.

Reducing risk of opioid addiction while alleviating pain

A preclinical trial has identified a way to thwart the highly addictive nature of opioids such as morphine and oxycodone while maintaining the drugs’ ability to relieve pain.

Sex differences in neuron protection could reveal Alzheimer’s target

Inhibiting an immune signaling protein may help preserve the protective layer surrounding nerve fibers in the brain during both Alzheimer’s disease and ordinary aging, a new study suggests.

Near ancient obelisk, AAP’s ‘Pyramidion’ towers at Met

The installation designed by AAP's Jennifer Newsom and Tom Carruthers is one of nearly 200 artworks featured in the Metropolitan Museum of Art's "Flight into Egypt: Black Artists and Ancient Egypt, 1876-Now" exhibition, open through Feb. 17.

What a gut fungus reveals about symbiosis, allergy

A fungus discovered in the mouse stomach may hold a key to fungal evolution within the gastrointestinal tract, according to new research led by Weill Cornell Medicine investigators.