Weill Cornell awarded $17.4M grant to develop shorter TB treatment regimen

The researchers aim to shift TB drug development toward creating new drugs from the start to work in the combinations needed to cure tuberculosis.

Uncovering hidden complexity in a key drug target for brain disorders

Metabotropic glutamate receptors interact in varied ways with their principal regulatory proteins, according to Weill Cornell Medicine investigators. The findings could inform treatments for epilepsy, depression and anxiety disorders.

Stress hormone timing creates a different kind of obesity

Obesity caused by disrupted stress-hormone rhythms is metabolically very different from obesity caused by a high-fat diet, according to new research.

Cornellians to address AI, NY energy future at Climate Week NYC

Cornell and global leaders will come together at Climate Week NYC Sept. 20-27 to discuss some of the world’s most pressing sustainability challenges, including harnessing AI’s power while mitigating its negative impacts.

Antifungal therapy restores gut microbiome in IBD patients

A commonly used systemic antifungal medication may help reduce symptoms in a subset of patients with inflammatory bowel disease.

Model helps scientists build better protein-degrading therapies

A team of Weill Cornell Medicine investigators has developed a computer model that will help scientists more efficiently develop protein-destroying therapies, a newer type of treatment that is particularly promising for cancer. 

Folic acid does not elevate formaldehyde in mice and humans

Folic acid does not elevate toxic formaldehyde in the body, according to a new study on mice and human cancer patients who consumed high doses. 

Developing a genetic toolkit for manipulating intestinal microbes

The ability to genetically manipulate these microbes could lead to a better understanding of the role they play in human physiology and diseases.

Researchers find new clue to prostate cancer’s hormone therapy resistance

Prostate tumors can rewire amino acid metabolism to override the normal brakes on cholesterol production, a process that may fuel hormone therapy resistance, according to Weill Cornell Medicine researchers.