Reducing risk of opioid addiction while alleviating pain

A preclinical trial has identified a way to thwart the highly addictive nature of opioids such as morphine and oxycodone while maintaining the drugs’ ability to relieve pain.

Sex differences in neuron protection could reveal Alzheimer’s target

Inhibiting an immune signaling protein may help preserve the protective layer surrounding nerve fibers in the brain during both Alzheimer’s disease and ordinary aging, a new study suggests.

Near ancient obelisk, AAP’s ‘Pyramidion’ towers at Met

The installation designed by AAP's Jennifer Newsom and Tom Carruthers is one of nearly 200 artworks featured in the Metropolitan Museum of Art's "Flight into Egypt: Black Artists and Ancient Egypt, 1876-Now" exhibition, open through Feb. 17.

What a gut fungus reveals about symbiosis, allergy

A fungus discovered in the mouse stomach may hold a key to fungal evolution within the gastrointestinal tract, according to new research led by Weill Cornell Medicine investigators.

Tirzepatide shows strong diabetes-prevention effect in trial

The new injectable weight-loss drug reduced the risk of diabetes in patients with obesity and prediabetes by more than 90% over a three-year period, compared with placebo.

Fighting aging by staying compact

The secret to cellular youth may depend on keeping the nucleolus – a condensed structure inside the nucleus of a cell – small, according to Weill Cornell Medicine investigators.

Treatment combination for subdural hematoma reduces recurrence risk

A novel combination of surgery and embolization used to treat subdural hematomas, bleeding between the brain and its protective membrane due to trauma, reduces the risk of follow-up surgeries, according to researchers at Weill Cornell Medicine and University at Buffalo.

New model of neuronal circuit provides insight on eye movement

Working with week-old zebrafish larva, researchers at Weill Cornell Medicine and colleagues decoded how the connections formed by a network of neurons in the brainstem guide the fishes’ gaze.

Key strategies unveiled against drug-resistant prostate cancer

An enzyme called EZH2 has an unexpected role in driving aggressive tumor growth in treatment-resistant prostate cancers, according to a new study by scientists at Weill Cornell Medicine.