Humanized mice reveal arsenic may raise diabetes risk only for males

A new study – using lab mice genetically modified with a human gene to shed light on a potential link between arsenic exposure and diabetes – revealed that while the male mice exposed to arsenic in drinking water developed diabetes, the female mice did not.

Mapping brain repair and remodeling after stroke

Researchers at Weill Cornell Medicine have catalogued the cellular response to stroke in a preclinical model, identifying the immune cells involved and the roles they may play in the days and weeks following a stroke.

Grant to validate blood test for early breast cancer detection

Weill Cornell Medicine researchers received a $2.4 million grant from the U.S. Department of Defense Breast Cancer Research Program to evaluate a test that uses an artificial intelligence algorithm to determine whether a patient is positive for cancer.

Grants will fund tuberculosis drug development

Weill Cornell Medicine researchers and the TB Drug Accelerator have received two grants totaling $6.8 million from the Bill & Melinda Gates Foundation to study tuberculosis drug development.

In chatty midshipman fish, the midbrain awakens a gift of gab

For talkative midshipman fish, the midbrain plays a key role in patterning trains of sounds and may serve as a model for how mammals, including humans, control vocal expression.

3D organization of DNA controls cell identity programs

A new study reveals that beyond providing a convenient way to store DNA in a tight space, the 3D organization of noncoding gene regulators in chromatin contributes to the control of key cell identity programs in early embryonic development.

New method could help estimate wildlife disease spread

A new method could be used by biologists to estimate the prevalence of disease in free-ranging wildlife and help determine how many samples are needed to detect a disease.

Aggressive colon tumor may be vulnerable to cholesterol therapy

A preclinical study has shown that colorectal pre-cancerous lesions known as serrated polyps, and the aggressive tumors that develop from them, depend on the ramped-up production of cholesterol, which points to the possibility of using cholesterol-lowering drugs to prevent or treat such tumors.

Discontinuing anti-obesity drug tirzepatide leads to weight regain

A clinical trial led by researchers at Weill Cornell Medicine and NewYork-Presbyterian found remaining on the anti-obesity drug tirzepatide promoted additional weight loss and preserved improvements in metabolic and cardiovascular health.